Ellen Yu Art
Three conditions are commonly associated with diabetic retinopathy: high blood pressure, high fat, and high glucose. These conditions are represented by the chemical structures of angiotensin, palmitic acid, and glucose respectively. These factors impacted gene expression, so I inserted them inside loops of DNA, similar to the function of histones. This led to phenotypic changes in mueller glia, astrocytes, and microglia resulting in an overall phenotype that closely resembles diabetic retinopathy.