Skylar Cuevas Art
Another research focus of the Byndloss Lab includes the connection between a high fat diet and E. coli choline catabolism. A high fat diet increases the bioavailability of nitrate and host-derived oxygen, leading to an expansion of E. coli. E. coli depends on nitrate for choline utilization, concluding that a high fat diet triggers choline catabolism by E. coli. This piece depicts a simplified version of the process beginning with diet and ending with catabolism in the gut.